Node.js requires a Hosting Business offer.
You can activate Node.js in your web.config by adding the handler "iisnode".
If the web.config file does not exist, you need to create it.
Example of a newly created configuration file:
<?xml version="1.0" encoding="UTF-8"?>
<configuration>
<system.webServer>
<handlers>
<add name="iisnode" path="HelloWorld.js" verb="*" modules="iisnode" />
</handlers>
</system.webServer>
</configuration>
Hint:
Visualstudio creates the necessary web.config automatically.